Brain membrane protein band 3 performs the same functions as erythrocyte band 3.

Polyphenols Inhibit Band 3 Protein of the Erythrocyte Membrane

The effect of selected potential inhibitors of anion transport mediated by the Band 3 protein of the erythrocyte membrane was studied by the electron spin resonance (ESR) technique using Tempo-phosphate spin probe. No inhibition of Band 3-mediated transport by 1-cyano-4-hydroxycinnamic acid, inhibitor of monocarboxylate transporters (MCT) was found but inhibition by some polyphenols (curcumin >...

Inducible expression of erythrocyte band 3 protein.

A permanent cell line with inducible expression of the human anion exchanger protein 1 (hAE1) was constructed in a derivative of human embryonic kidney cells (HEK-293). In the absence of the inducer, muristerone A, the new cell line had no detectable hAE1 protein by Western analysis or additional36Cl flux. Increasing dose and incubation time with muristerone A increased the amount of protein (b...

EPB 41 L 3 ( erythrocyte membrane protein band 4 . 1 - like 3 )

Phosphotyrosine phosphatase associated with band 3 protein in the human erythrocyte membrane.

The anion-exchange band 3 protein is the main erythrocyte protein that is phosphorylated by tyrosine kinase. To study the regulation of band 3 phosphorylation, we examined phosphotyrisine phosphatase (PTP) activity in the human erythrocyte. We show that the human erythrocyte membrane contains a band 3-associated neutral PTP which is activated by Mg2+ and inhibited by Mn2+ and vanadate. The PTP ...

Hereditary spherocytosis associated with a variant of band 3 protein in the erythrocyte membrane.

A 17-year-old woman with hereditary spherocytosis was found to be heterozygous for an unusual variant of the band 3 protein in erythrocyte membranes. The variant had a molecular weight of 95,000 daltons which was larger by about 3,000 daltons than the 92,000 m.w. normal band 3, and was phosphorylated less efficiently when intact cells were incubated with 32P-inorganic phosphate. It is discussed...